Multimodal oncosurgery approach to treat peritoneal carcinomatosis in a patient with occlusive ovarian carcinoma

Eur J Gynaecol Oncol. 2016;37(2):251-3.

Abstract

Summary

Background: This paper aims to present a "pattern" of oncosurgery solution in a case generally considered unrecoverable: intestinal occlusion in case of ovarian carcinoma and carcinomatosis.

Case report: A 62-year-old female patient with ascites, carcinomatosis, unresectable pelvic tumour, and intestinal obstruction suffered a five-step oncosurgery "model": three surgical interventions overlapping chemotherapy administered via the systemic and intraperitoneal route: Step 1: colostomy and partial omentectomy; Step 2: five courses of systemic chemotherapy supported by granulocyte colony-stimulating factor; Step 3: radical surgery--total hysterectomy, bilateral adnexectomy, pelvic lymphadenectomy, omentectomy, appendectomy, pelvic peritonectomy, and hyperthermic intraperitoneal chemotherapy; Step 4: consolidation systemic chemotherapy consisting of three more similar cycles; Step 5: closure of the colostomy. Nine months after the beginning of treatment, the patient is with no evidence of disease.

Conclusions: The association of surgical and oncologic treatment and the use of hyperthermic intraperitoneal chemotherapy (HIPEC) technology can solve some of these complex cases.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Carcinoma / complications
  • Carcinoma / pathology
  • Carcinoma / therapy*
  • Colostomy
  • Consolidation Chemotherapy
  • Cytoreduction Surgical Procedures
  • Female
  • Humans
  • Hyperthermia, Induced
  • Hysterectomy
  • Infusions, Parenteral
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / surgery*
  • Lymph Node Excision
  • Middle Aged
  • Omentum / surgery*
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / therapy*
  • Ovariectomy
  • Peritoneal Neoplasms / secondary
  • Peritoneal Neoplasms / therapy*
  • Peritoneum / surgery*
  • Salpingectomy

Substances

  • Antineoplastic Agents