Visible-Light Induced Direct Synthesis of Polysubstituted Furans from Cyclopropyl Ketones

J Org Chem. 2016 Aug 19;81(16):7008-22. doi: 10.1021/acs.joc.6b00436. Epub 2016 May 19.

Abstract

In this article, a photoredox protocol for the synthesis of furans via oxidative coupling of olefin generated in situ from cyclopropyl ketones with ketonic oxygen atom is presented. Moreover, bromination of furans in the presence of overstoichiometric oxidant has been achieved with high regioselectivity.

Publication types

  • Research Support, Non-U.S. Gov't