Abstract
Attempts were made to enhance the sensitivity of immuno-PCR assay based on the detection of cocktail of mycobacterial antigen 85B (Rv1886c), ESAT-6 (Rv3875) and cord factor (trehalose 6,6'-dimycolate) in pulmonary and extrapulmonary TB patients. Detection of Ag85B was found to be superior to the detection of cocktail in TB patients.
Keywords:
Antigen 85B; Cord factor; ESAT-6; Immuno-PCR; Tuberculosis.
Copyright © 2016 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antigens, Bacterial / analysis*
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Antigens, Bacterial / immunology
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Cord Factors / analysis*
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Cord Factors / immunology
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Immunoassay / methods
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Polymerase Chain Reaction / methods*
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Tuberculosis / diagnosis*
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Tuberculosis / microbiology
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Tuberculosis, Pulmonary / diagnosis
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Tuberculosis, Pulmonary / microbiology
Substances
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Antigens, Bacterial
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Cord Factors
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ESAT-6 antigen, Mycobacterium leprae
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antigen 85B, Mycobacterium leprae