Potential Use of Fosfomycin-Tromethamine for Treatment of Recurrent Campylobacter Species Enteritis

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4398-400. doi: 10.1128/AAC.00447-16. Print 2016 Jul.

Abstract

We report 2 cases of recurrent Campylobacter coli enteritis caused by macrolide- and fluoroquinolone-resistant strains in 2 patients with hypogammaglobulinemia, successfully treated with a prolonged course of fosfomycin-tromethamine with no side effects. Fosfomycin-tromethamine may be a feasible alternative therapy for recurrent enteritis caused by Campylobacter species resistant to first-line drugs.

Publication types

  • Case Reports

MeSH terms

  • Agammaglobulinemia / drug therapy
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Campylobacter / drug effects*
  • Campylobacter / pathogenicity*
  • Enteritis / drug therapy*
  • Female
  • Fosfomycin / therapeutic use*
  • Humans
  • Microbial Sensitivity Tests
  • Middle Aged
  • Tromethamine / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Tromethamine
  • Fosfomycin

Grants and funding

This research received no specific grant from any funding agency in the public, commercial, or nonprofit sectors.