Abstract
Phenoxazines are an important class of heterocycles, which are emerging in the field of medicinal chemistry. They exhibit numerous biological activities, including antiviral, anticancer, anti-Alzheimer, antidiabetic, antioxidant, anti-inflammatory, antibiotic and many more. The present review focuses on the chemistry along with the medicinal applications of the phenoxazine moiety, in order to provide a greater insight for the development of future phenoxazine therapeutics.
MeSH terms
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Animals
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Anti-Bacterial Agents / chemical synthesis*
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / therapeutic use
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Antineoplastic Agents / toxicity
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Apoptosis / drug effects
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Bacterial Proteins / metabolism
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Mycobacterium / drug effects
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Neoplasms / drug therapy
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Oxazines / chemical synthesis
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Oxazines / chemistry*
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Oxazines / metabolism
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Oxidoreductases / metabolism
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Streptomyces / enzymology
Substances
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Anti-Bacterial Agents
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Antineoplastic Agents
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Bacterial Proteins
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Oxazines
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phenoxazine
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Oxidoreductases
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2-aminophenol oxidase