Clinical and Research Applications of Quantitative PET Imaging

Sandip Basu; Habib Zaidi; Abass Alavi

doi:10.1016/j.cpet.2007.10.002

Clinical and Research Applications of Quantitative PET Imaging

PET Clin. 2007 Apr;2(2):161-72. doi: 10.1016/j.cpet.2007.10.002. Epub 2008 Feb 15.

Authors

Sandip Basu¹, Habib Zaidi², Abass Alavi³

Affiliations

¹ Department of Radiology, Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA.
² Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva, Switzerland.
³ Department of Radiology, Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA. Electronic address: abass.alavi@uphs.upenn.edu.

PMID: 27157871
DOI: 10.1016/j.cpet.2007.10.002

Abstract

In recent years, three important quantitative concepts in PET analysis have been developed: partial volume correction of standardized uptake value (SUV) in small lesions, dual-time point and delayed PET imaging, and assessment of global metabolic activity in the whole organ or of a particular diseased tissue(s). In this article, we discuss these novel concepts, their advantages over current quantitative techniques, and their potential clinical applications. We also describe the complicated kinetic modeling and the conventional SUV methods that have been used in the practice of clinical PET.

Publication types

Review