Role of Global Disease Assessment by Combined PET-CT-MR Imaging in Examining Cardiovascular Disease

Babak Saboury; Pouya Ziai; Abass Alavi

doi:10.1016/j.cpet.2011.10.003

Role of Global Disease Assessment by Combined PET-CT-MR Imaging in Examining Cardiovascular Disease

PET Clin. 2011 Oct;6(4):421-9. doi: 10.1016/j.cpet.2011.10.003. Epub 2011 Nov 24.

Authors

Babak Saboury¹, Pouya Ziai, Abass Alavi

Affiliation

¹ Department of Radiology, School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.

PMID: 27156877
DOI: 10.1016/j.cpet.2011.10.003

Abstract

Atherosclerosis is considered a chronic inflammatory disease, and thereafter the degree of this pathologic process is considered to be a major determinant in plaque stability and in forecasting future events. Over the past decade, (18)F-fluorodeoxyglucose PET/computed tomography has become a well-established imaging modality in evaluating various inflammatory disorders, and has been shown to be very useful in evaluating plaque activity in major arteries. This emerging noninvasive imaging modality has great potential in evaluating plaque vulnerability and in predicting the risk of future rupture and consequent thrombosis.