Primary Cancer of the Liver and Biliary Duct

Jong Doo Lee; Won Jun Kang; Mijin Yun

doi:10.1016/j.cpet.2008.08.005

Primary Cancer of the Liver and Biliary Duct

PET Clin. 2008 Apr;3(2):169-86. doi: 10.1016/j.cpet.2008.08.005. Epub 2008 Dec 6.

Authors

Jong Doo Lee¹, Won Jun Kang², Mijin Yun²

Affiliations

¹ Division of Nuclear Medicine, Department of Diagnostic Radiology, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul 120-752, South Korea. Electronic address: jdlee@yuhs.ac.
² Division of Nuclear Medicine, Department of Diagnostic Radiology, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul 120-752, South Korea.

PMID: 27156461
DOI: 10.1016/j.cpet.2008.08.005

Abstract

F-18-FDG PET and PET/CT are useful for staging, predicting the prognosis, and evaluating recurrence and treatment response in hepatocellular carcinomas (HCCs) and cholangiocarcinomas. Increased F-18-FDG uptake within tumors could be a surrogate marker of aggressive behavior and poor clinical outcome, despite high false-negative rates in detecting primary intrahepatic low-grade HCCs and periductal-infiltrating cholangiocarcinomas. Dualtracer PET or PET/CT using carbon-11-acetate and F-18-FDG will increase diagnostic performance in HCC.

Keywords: Acetate; Cholangiocarcinoma; Fluorodeoxyglucose; Hepatocellular carcinoma; Positron emission tomography.

Publication types

Review