Curcumin bioavailability from oil in water nano-emulsions: In vitro and in vivo study on the dimensional, compositional and interactional dependence

J Control Release. 2016 Jul 10:233:88-100. doi: 10.1016/j.jconrel.2016.05.004. Epub 2016 May 4.

¹ Center for Advanced Biomaterials for Health Care@CRIB, Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci 53, Napoli 80125, Italy; Interdisciplinary Research Center of Biomaterials, CRIB, University Federico II, P.le Tecchio, 80, 80125 Naples, Italy.
² Medical Oncology, Abdominal Department, National Cancer Institute G. Pascale Foundation, Napoli 80131, Italy.
³ Interdisciplinary Research Center of Biomaterials, CRIB, University Federico II, P.le Tecchio, 80, 80125 Naples, Italy.
⁴ Center for Bio-Molecular Nanotechnologies@UniLe, Istituto Italiano di Tecnologia, Via Barsanti, 73010 Arnesano (Lecce), Italy.
⁵ Medical Oncology, Abdominal Department, National Cancer Institute G. Pascale Foundation, Napoli 80131, Italy. Electronic address: r.iaffaioli@istitutotumori.na.it.
⁶ Center for Advanced Biomaterials for Health Care@CRIB, Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci 53, Napoli 80125, Italy; Interdisciplinary Research Center of Biomaterials, CRIB, University Federico II, P.le Tecchio, 80, 80125 Naples, Italy. Electronic address: paolo.netti@iit.it.

No abstract available

Keywords: 2-Iminothiolane; Chitosan; Colon cancer; Curcumin; Nano-emulsions; Piperine.

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