CellMiner Companion: an interactive web application to explore CellMiner NCI-60 data

Sufang Wang; Michael Gribskov; Tony R Hazbun; Pete E Pascuzzi

doi:10.1093/bioinformatics/btw162

CellMiner Companion: an interactive web application to explore CellMiner NCI-60 data

Bioinformatics. 2016 Aug 1;32(15):2399-401. doi: 10.1093/bioinformatics/btw162. Epub 2016 Mar 25.

Authors

Sufang Wang¹, Michael Gribskov¹, Tony R Hazbun², Pete E Pascuzzi³

Affiliations

¹ Department of Biological Sciences.
² Department of Medicinal Chemistry and Molecular Pharmacology Purdue University Center for Cancer Research.
³ Purdue University Center for Cancer Research Department of Biochemistry Purdue University Libraries, Purdue University, West Lafayette, IN 47907, USA.

PMID: 27153600
DOI: 10.1093/bioinformatics/btw162

Abstract

The NCI-60 human tumor cell line panel is an invaluable resource for cancer researchers, providing drug sensitivity, molecular and phenotypic data for a range of cancer types. CellMiner is a web resource that provides tools for the acquisition and analysis of quality-controlled NCI-60 data. CellMiner supports queries of up to 150 drugs or genes, but the output is an Excel file for each drug or gene. This output format makes it difficult for researchers to explore the data from large queries. CellMiner Companion is a web application that facilitates the exploration and visualization of output from CellMiner, further increasing the accessibility of NCI-60 data.

Availability and implementation: The web application is freely accessible at https://pul-bioinformatics.shinyapps.io/CellMinerCompanion The R source code can be downloaded at https://github.com/pepascuzzi/CellMinerCompanion.git

Contact: ppascuzz@purdue.edu

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

Cell Line, Tumor*
Humans
Internet
Software
User-Computer Interface*