DNATCO: assignment of DNA conformers at dnatco.org

Nucleic Acids Res. 2016 Jul 8;44(W1):W284-7. doi: 10.1093/nar/gkw381. Epub 2016 May 5.

Abstract

The web service DNATCO (dnatco.org) classifies local conformations of DNA molecules beyond their traditional sorting to A, B and Z DNA forms. DNATCO provides an interface to robust algorithms assigning conformation classes called NTC: to dinucleotides extracted from DNA-containing structures uploaded in PDB format version 3.1 or above. The assigned dinucleotide NTC: classes are further grouped into DNA structural alphabet NTA: , to the best of our knowledge the first DNA structural alphabet. The results are presented at two levels: in the form of user friendly visualization and analysis of the assignment, and in the form of a downloadable, more detailed table for further analysis offline. The website is free and open to all users and there is no login requirement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Computer Graphics
  • DNA / chemistry*
  • Information Storage and Retrieval
  • Internet
  • Nucleic Acid Conformation
  • Software*

Substances

  • DNA