Pixel-by-Pixel Arterial Spin Labeling Blood Flow Pattern Variation Analysis for Discrimination of Rheumatoid Synovitis: A Pilot Study

Magn Reson Med Sci. 2017 Jan 10;16(1):78-83. doi: 10.2463/mrms.tn.2015-0145. Epub 2016 May 6.

Abstract

We examined the capability of a gray-scale arterial spin labeling blood flow pattern variation (BFPV) map with two different post labeling delay (PLD) times to discriminate pannus in patients with rheumatoid arthritis (RA) at 3T. There was a statistically significant difference in the BFPV values between artery, pannus, and surrounding tissue. Furthermore, the color-coded BFPV map was able to accurately distinguish pannus from other tissues. These results suggest this approach may be capable of identifying pannus noninvasively.

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / complications*
  • Arthritis, Rheumatoid / diagnostic imaging*
  • Diagnosis, Differential
  • Female
  • Finger Joint / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Pilot Projects
  • Spin Labels*
  • Synovitis / complications*
  • Synovitis / diagnostic imaging*
  • Wrist Joint / diagnostic imaging

Substances

  • Spin Labels