[Biochemical markers of bone metabolism and their importance]

Z Rheumatol. 2016 Jun;75(5):451-8. doi: 10.1007/s00393-016-0083-5.
[Article in German]

Abstract

Laboratory analyses of biochemical markers for bone and mineral metabolism can play a key role in the assessment of patients with osteoporosis. They may help to assess bone turnover in the diagnostic work-up and aid decision-making as well as selection of pharmaceutical therapy options. Recent publications on therapy response have shown that biochemical markers of bone turnover are valuable tools for the evaluation of therapy success in individual osteoporosis patients and the assessment of bone mineral density gain during therapy.

Keywords: Biomarkers; Laboratory analyses; Monitoring; Osteoporosis; Therapy.

Publication types

  • Review

MeSH terms

  • Biomarkers / blood
  • Bone and Bones / metabolism
  • Collagen / blood*
  • Humans
  • Osteoporosis / blood*
  • Osteoporosis / diagnosis*
  • Osteoporosis / drug therapy
  • Peptide Fragments / blood*
  • Procollagen / blood*
  • Tartrate-Resistant Acid Phosphatase / blood*
  • Vitamin D / blood*

Substances

  • Biomarkers
  • Peptide Fragments
  • Procollagen
  • procollagen Type I N-terminal peptide
  • Vitamin D
  • Collagen
  • Tartrate-Resistant Acid Phosphatase