Rapid Prototyping of Chemical Microsensors Based on Molecularly Imprinted Polymers Synthesized by Two-Photon Stereolithography

Laura Piedad Chia Gomez; Arnaud Spangenberg; Xuan-Anh Ton; Yannick Fuchs; Frank Bokeloh; Jean-Pierre Malval; Bernadette Tse Sum Bui; Damien Thuau; Cédric Ayela; Karsten Haupt; Olivier Soppera

doi:10.1002/adma.201600218

Rapid Prototyping of Chemical Microsensors Based on Molecularly Imprinted Polymers Synthesized by Two-Photon Stereolithography

Adv Mater. 2016 Jul;28(28):5931-7. doi: 10.1002/adma.201600218. Epub 2016 May 4.

Affiliations

¹ Institut de Science des Matériaux de Mulhouse (IS2M), CNRS - UMR 7361, Université de Haute Alsace, 15 rue Jean Starcky, Mulhouse, 68057, France.
² Sorbonne Universités, Université de Technologie de Compiègne, CNRS Laboratory for Enzyme and Cell Engineering, Rue Roger Couttolenc, CS 60319, 60203, Compiègne, France.
³ Laboratoire de L'Intégration du Matériau au Système, Université de Bordeaux, 351 Cours de la Libération, 33405, Talence cedex, France.

PMID: 27145145
DOI: 10.1002/adma.201600218

Abstract

Two-photon stereolithography is used for rapid prototyping of submicrometre molecularly imprinted polymer-based 3D structures. The structures are evaluated as chemical sensing elements and their specific recognition properties for target molecules are confirmed. The 3D design capability is exploited and highlighted through the fabrication of an all-organic molecularly imprinted polymeric microelectromechanical sensor.

Keywords: 3D microfabrication; chemical sensors; microelectromechanical systems; molecularly imprinted polymers; two-photon polymerization.