Early Transthoracic Echocardiography after Cardiac Surgery Predicts Postoperative Atrial Fibrillation

Echocardiography. 2016 Sep;33(9):1300-8. doi: 10.1111/echo.13254. Epub 2016 May 4.

Abstract

Purpose: Postoperative atrial fibrillation (POAF) is frequent after cardiac surgery. We aimed to establish a predictive model of POAF based on postoperative transthoracic echocardiography (TTE) findings.

Methods: This study included 147 patients (aged 67 ± 11 years; 109 men) undergoing coronary artery bypass grafting and/or aortic valve replacement. TTE and Doppler tissue imaging were performed on intensive care unit arrival after surgery. All patients were continuously monitored during hospitalization. The end point was the appearance of POAF.

Results: POAF appeared in 37 patients (25.2%). These patients were older (69 ± 16 vs. 65 ± 12 years; P < 0.001) and had increased long axis of the left atrium (LA) dimension (5.4 ± 1 vs. 4.8 ± 0.9 cm, P = 0.02), lower early diastolic velocity of the mitral annulus (e') (6.9 ± 2.1 vs. 8 ± 1.8 cm/sec; P < 0.01), and higher early diastolic pulsed Doppler mitral ratio (E)/e' (E/e') (17.4 ± 6.8 vs. 13.8 ± 6; P = 0.01). Left ventricle diastolic dysfunction grade (DFG) of 2 or 3 relative to grade 0 was significant: odds ratio (OR) 22.5, 95% confidence interval (CI) 4.52-57.2; P < 0.001, and OR: 23.6, 95% CI: 3.57-60.1; P = 0.001), respectively. On multivariate analysis, the independent predictors of POAF were age (OR: 1.10, 95% CI: 1.01-1.18; P < 0.05), long-axis LA dimension (OR: 6.24, 95% CI: 1.97-8.23; P = 0.0017), DFG-2 (OR: 4.1, 95% CI: 1.57-15.81; P < 0.001), and DFG-3 (OR: 8.3, 95% CI: 4.11-25.37; P < 0.001).

Conclusions: Apart from age, the simple determination by postoperative TTE of long-axis LA dimension and DFG after cardiac surgery proved to be powerful independent predictors of POAF and may be useful for risk stratification of these patients.

Keywords: aortic valve replacement; cardiac surgery; coronary artery bypass graft surgery; echocardiography; postoperative atrial fibrillation.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Atrial Fibrillation / diagnostic imaging*
  • Atrial Fibrillation / mortality*
  • Cardiac Surgical Procedures / mortality*
  • Cardiac Surgical Procedures / statistics & numerical data
  • Causality
  • Comorbidity
  • Early Diagnosis
  • Echocardiography / methods
  • Echocardiography / statistics & numerical data
  • Elasticity Imaging Techniques / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Male
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / mortality*
  • Prognosis
  • Reproducibility of Results
  • Risk Factors
  • Sensitivity and Specificity
  • Spain / epidemiology
  • Survival Rate
  • Treatment Outcome
  • Ventricular Dysfunction, Left / diagnostic imaging*
  • Ventricular Dysfunction, Left / mortality*