Nanometric resolution magnetic resonance imaging methods for mapping functional activity in neuronal networks

Albert Boretti; Stefania Castelletto

doi:10.1016/j.mex.2016.04.003

Nanometric resolution magnetic resonance imaging methods for mapping functional activity in neuronal networks

MethodsX. 2016 Apr 16:3:297-306. doi: 10.1016/j.mex.2016.04.003. eCollection 2016.

Authors

Albert Boretti¹, Stefania Castelletto²

Affiliations

¹ Department of Mechanical and Aerospace Engineering (MAE), Benjamin M. Statler College of Engineering and Mineral Resources, West Virginia University (WVU), P.O. Box 6106, 325 Engineering Sciences Building, Morgantown, WV 26506, United States.
² School of Engineering, RMIT University, Bundoora, VIC 3083, Australia.

Abstract

This contribution highlights and compares some recent achievements in the use of k-space and real space imaging (scanning probe and wide-filed microscope techniques), when applied to a luminescent color center in diamond, known as nitrogen vacancy (NV) center. These techniques combined with the optically detected magnetic resonance of NV, provide a unique platform to achieve nanometric magnetic resonance imaging (MRI) resolution of nearby nuclear spins (known as nanoMRI), and nanometric NV real space localization. •Atomic size optically detectable spin probe.•High magnetic field sensitivity and nanometric resolution.•Non-invasive mapping of functional activity in neuronal networks.

Keywords: Magnetic resonance imaging; Nano Fourier magnetic resonance imaging; Nano scale; Neuronal networks; Nitrogen vacancy in diamond; Optical detection; Super-resolution microscopy.