Improving the antioxidant activity and enriching salvianolic acids by the fermentation of Salvia miltiorrhizae with Geomyces luteus

J Zhejiang Univ Sci B. 2016 May;17(5):391-8. doi: 10.1631/jzus.B1500264.

Abstract

The antioxidant activities and total phenolic content of fermented Salvia miltiorrhiza with fungus Geomyces luteus were investigated. The results revealed that G. luteus fermentation could significantly improve the antioxidant activity and total phenolic content of S. miltiorrhiza. The main antioxidant constituents were characterized by spectroscopic analysis as salvianolic acids. High-performance liquid chromatography (HPLC) quantification also showed the enhanced content of salvianolic acid B after fermentation. The present study suggests that G. luteus fermentations are effective in the S. miltiorrhiza salvianolic acids' enrichment process.

Keywords: Antioxidant; Fermentation; Geomyces luteus; Salvia miltiorrhiza; Salvianolic acids.

MeSH terms

  • Alkenes / chemistry*
  • Antioxidants / chemistry*
  • Ascomycota / metabolism*
  • Benzofurans / chemistry
  • Biphenyl Compounds / chemistry
  • Chromatography, High Pressure Liquid
  • Drugs, Chinese Herbal / chemistry
  • Fermentation*
  • Phenols / chemistry
  • Picrates / chemistry
  • Polyphenols / chemistry*
  • Salvia miltiorrhiza / chemistry*
  • Spectrophotometry, Ultraviolet
  • Spectroscopy, Fourier Transform Infrared

Substances

  • Alkenes
  • Antioxidants
  • Benzofurans
  • Biphenyl Compounds
  • Drugs, Chinese Herbal
  • Phenols
  • Picrates
  • Polyphenols
  • salvianolic acid
  • salvianolic acid B
  • 1,1-diphenyl-2-picrylhydrazyl