Imaging findings, diagnosis, and clinical outcomes in patients with mycotic aneurysms: single center experience

Amy R Deipolyi; Alexander Bailin; Ali Khademhosseini; Rahmi Oklu

doi:10.1016/j.clinimag.2015.12.002

Imaging findings, diagnosis, and clinical outcomes in patients with mycotic aneurysms: single center experience

Clin Imaging. 2016 May-Jun;40(3):512-6. doi: 10.1016/j.clinimag.2015.12.002. Epub 2015 Dec 8.

Authors

Amy R Deipolyi¹, Alexander Bailin², Ali Khademhosseini³, Rahmi Oklu⁴

Affiliations

¹ Division of Vascular and Interventional Radiology, Department of Radiology, New York University Medical Center, New York, NY.
² Massachusetts General Hospital, Harvard Medical School, Vascular and Interventional Radiology, Boston, MA.
³ Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA.
⁴ Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA; Mayo Clinic, Division of Vascular and Interventional Radiology, Scottsdale, AZ. Electronic address: oklu.rahmi@mayo.edu.

PMID: 27133696
DOI: 10.1016/j.clinimag.2015.12.002

Abstract

Purpose: To review the presentation, imaging, clinical management, and outcomes in patients with mycotic aneurysm (MA).

Methods: Fifty-five cases in 49 patients (33 men, 16 women, average age: 66.2years) were identified.

Results: Of 49 patients, only 20% presented with the classic clinical triad of fever, elevated white count, and pain. Computed tomography was the most utilized imaging modality; focal vascular outpouching was the most frequent imaging finding (76%). There was 17% mortality rate within 6months of diagnosis despite intervention.

Conclusions: Clinical presentation and blood cultures can be nonspecific, highlighting the importance of imaging diagnosis of MA to expedite treatment.

Keywords: Mycotic aneurysm; diagnosis; imaging; infection.

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Aneurysm, Infected / diagnosis
Aneurysm, Infected / diagnostic imaging*
Aneurysm, Infected / mortality
Aneurysm, Infected / therapy
Female
Follow-Up Studies
Humans
Male
Middle Aged
Retrospective Studies
Tomography, X-Ray Computed*
Treatment Outcome
Young Adult