Reticulon-4B/Nogo-B acts as a molecular linker between microtubules and actin cytoskeleton in vascular smooth muscle cells

Biochim Biophys Acta. 2016 Aug;1863(8):1985-95. doi: 10.1016/j.bbamcr.2016.04.025. Epub 2016 Apr 28.
No abstract available

Keywords: Cytoskeleton; HDAC-6; Nogo-B; Rho A; VSMCs; Vascular remodeling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylation
  • Actin Cytoskeleton / metabolism*
  • Actin Cytoskeleton / ultrastructure
  • Actins / analysis
  • Animals
  • Aorta
  • Cell Movement
  • Cell Size
  • Cells, Cultured
  • Chemotaxis
  • Cytoskeleton / metabolism
  • Cytoskeleton / ultrastructure
  • Endoplasmic Reticulum / chemistry
  • Focal Adhesions
  • Histone Deacetylase 6
  • Histone Deacetylases / metabolism
  • Male
  • Microtubules / metabolism*
  • Muscle, Smooth, Vascular / cytology*
  • Myocytes, Smooth Muscle / metabolism*
  • Myocytes, Smooth Muscle / ultrastructure
  • Nogo Proteins / antagonists & inhibitors
  • Nogo Proteins / genetics
  • Nogo Proteins / physiology*
  • Protein Processing, Post-Translational
  • RNA Interference
  • Rats
  • Rats, Sprague-Dawley
  • Tubulin / metabolism
  • rho GTP-Binding Proteins / metabolism

Substances

  • Actins
  • Nogo Proteins
  • Rtn4 protein, rat
  • Tubulin
  • HDAC6 protein, rat
  • Histone Deacetylase 6
  • Histone Deacetylases
  • RhoA protein, rat
  • rho GTP-Binding Proteins