APASL consensus statements and recommendation on treatment of hepatitis C

Masao Omata; Tatsuo Kanda; Lai Wei; Ming-Lung Yu; Wang-Long Chuang; Alaaeldin Ibrahim; Cosmas Rinaldi Adithya Lesmana; Jose Sollano; Manoj Kumar; Ankur Jindal; Barjesh Chander Sharma; Saeed S Hamid; A Kadir Dokmeci; Mamun-Al-Mahtab; Geofferey W McCaughan; Jafri Wasim; Darrell H G Crawford; Jia-Horng Kao; Osamu Yokosuka; George K K Lau; Shiv Kumar Sarin

doi:10.1007/s12072-016-9717-6

APASL consensus statements and recommendation on treatment of hepatitis C

Hepatol Int. 2016 Sep;10(5):702-26. doi: 10.1007/s12072-016-9717-6. Epub 2016 Apr 29.

Authors

Masao Omata^{1

2}, Tatsuo Kanda³, Lai Wei⁴, Ming-Lung Yu⁵, Wang-Long Chuang⁶, Alaaeldin Ibrahim⁷, Cosmas Rinaldi Adithya Lesmana⁸, Jose Sollano⁹, Manoj Kumar¹⁰, Ankur Jindal¹⁰, Barjesh Chander Sharma¹¹, Saeed S Hamid¹², A Kadir Dokmeci¹³, Mamun-Al-Mahtab¹⁴, Geofferey W McCaughan¹⁵, Jafri Wasim¹², Darrell H G Crawford¹⁶, Jia-Horng Kao¹⁷, Osamu Yokosuka³, George K K Lau¹⁸, Shiv Kumar Sarin¹⁰

Affiliations

¹ Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi, Kofu-Shi, Yamanashi, 400-8506, Japan. hepint_omata@yahoo.co.jp.
² The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. hepint_omata@yahoo.co.jp.
³ Graduate School of Medicine, Chiba University, Chiba, Japan.
⁴ Peking University Hepatology Institute, Peking University People's Hospital, Beijing, China.
⁵ Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.
⁶ Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
⁷ GI/Liver Division, Department of Internal Medicine, University of Benha, Benha, Egypt.
⁸ Digestive Disease and GI Oncology Center, Medistra Hospital, University of Indonesia, Jakarta, Indonesia.
⁹ University Santo Tomas Hospital, Manila, Philippines.
¹⁰ Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
¹¹ Department of Gastroenterology, G.B. Pant Hospital, New Delhi, India.
¹² Department of Medicine, Aga Khan University and Hospital, Stadium Road, Karachi, 74800, Pakistan.
¹³ Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
¹⁴ Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, 1000, Bangladesh.
¹⁵ Centenary Institute, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia.
¹⁶ School of Medicine, University of Queensland, Woolloongabba, QLD, 4102, Australia.
¹⁷ National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
¹⁸ The Institute of Translational Hepatology, Beijing 302 Hospital, Beijing, China.

Abstract

The Asian-Pacific Association for the Study of the Liver (APASL) convened an international working party on the "APASL consensus statements and recommendation on management of hepatitis C" in March, 2015, in order to revise "APASL consensus statements and management algorithms for hepatitis C virus infection (Hepatol Int 6:409-435, 2012)". The working party consisted of expert hepatologists from the Asian-Pacific region gathered at Istanbul Congress Center, Istanbul, Turkey on 13 March 2015. New data were presented, discussed and debated to draft a revision. Participants of the consensus meeting assessed the quality of cited studies. Finalized recommendations on treatment of hepatitis C are presented in this review.

Keywords: APASL; DAAs; HCV; Interferon-free; Turkey.

Publication types

Consensus Development Conference
Editorial
Practice Guideline
Review

MeSH terms

Antiviral Agents / administration & dosage*
Antiviral Agents / pharmacology
Clinical Trials as Topic
Disease Management
Hepacivirus / drug effects
Hepacivirus / genetics*
Hepatitis C, Chronic / drug therapy*
Hepatitis C, Chronic / virology
Humans
Practice Guidelines as Topic
Treatment Outcome
Viral Load / drug effects

Substances

Antiviral Agents