Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors

Int J Cardiol. 2016 Jul 15:215:201-8. doi: 10.1016/j.ijcard.2016.04.077. Epub 2016 Apr 17.

¹ Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
² Department of Health Promotion, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
³ Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
⁴ Department of Principles of Clinical Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland. Electronic address: piotr.adamski@wp.eu.
⁵ Department of Internal Medicine, Division of Cardiology, Pulmonology and Vascular Medicine, Heinrich-Heine-University, Düsseldorf, Germany.
⁶ Department of Cardiology, Medical University of Vienna, Vienna, Austria.
⁷ Department of Theoretical Foundations of Biomedical Science and Medical Informatics, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
⁸ Department of Principles of Clinical Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
⁹ Inova Center for Thrombosis Research and Drug Development, Inova Heart and Vascular Institute, Fairfax, VA, USA.

No abstract available

Keywords: Clopidogrel; Drug–drug interaction; Morphine; Prasugrel; Ticagrelor.

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