Usefulness of basic renal function tests in decision-making in children with loss of renal parenchyma and/or dilation of the urinary tract

Nefrologia. 2016 May-Jun;36(3):222-31. doi: 10.1016/j.nefro.2016.01.009. Epub 2016 Apr 25.
[Article in English, Spanish]

Abstract

Basic renal function tests such as maximum urine osmolality and urinary elimination of albumin and N-acetyl-glucosaminidase often reveal abnormalities in clinical cases involving hyperpressure in the urinary tract or loss of renal parenchyma. However, in all the available algorithms dedicated to the study of children with urinary tract infection or dilation, the benefit of using these functional parameters is not mentioned. In this review, we provide information about the practical usefulness of assessing the basic renal function parameters. From these data, we propose an algorithm that combines morphological and functional parameters to make a reasoned case for voiding cystourethrography.

Keywords: Albuminuria; Capacidad de concentración; Cistografía; Concentrating capacity; Cystourethrography; N-acetil-glucosaminidasa; N-acetyl-glucosaminidase; Reflujo vesicoureteral; Vesicoureteral reflux.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Algorithms
  • Child
  • Clinical Decision-Making*
  • Diagnostic Techniques, Urological
  • Dilatation, Pathologic / diagnosis
  • Dilatation, Pathologic / physiopathology
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Kidney / abnormalities
  • Kidney / diagnostic imaging
  • Kidney / pathology*
  • Kidney Concentrating Ability
  • Kidney Function Tests* / history
  • Osmolar Concentration
  • Urinalysis
  • Urinary Tract / abnormalities
  • Urinary Tract / diagnostic imaging
  • Urinary Tract / pathology*
  • Urinary Tract Infections / complications
  • Urology / history
  • Urology / methods
  • Vesico-Ureteral Reflux / diagnosis
  • Vesico-Ureteral Reflux / etiology