Cardiac resynchronization therapy (CRT) is currently an established device therapy for heart failure (HF) patients. Existing knowledge of implantation techniques, advances in device-based technologies and clinical trial experience have all significantly impacted this evolving therapy in recent years. This review article will address the updated CRT guidelines, and potentially new indications for CRT such as patients with mild HF symptoms and prolonged QRS duration; it also highlights new approaches for placement of the left ventricular (LV) lead, multi-site LV pacing, and the role of automatic device optimization in CRT.
Key words: Cardiac resynchronization therapy; Guideline; Heart failure; Optimization.