Mevastatin suppresses melanogenesis by lowering the levels of cyclic adenosine monophosphate and cholesterol

Exp Dermatol. 2016 Oct;25(10):820-2. doi: 10.1111/exd.13056. Epub 2016 Jul 13.

Authors

Heun Joo Lee¹, Soo Youn Jo², Jae Sung Hwang³, Sung Eun Chang⁴

Affiliations

¹ Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
² Asan Institute for Life Science, Seoul, Korea.
³ Department of Genetic Engineering, College of Life Sciences, Kyung Hee University, Yongin, Korea. jshwang@khu.ac.kr.
⁴ Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. csesnumd@gmail.com.

PMID: 27119271
DOI: 10.1111/exd.13056

No abstract available

Keywords: cholesterol; cyclic AMP; melanogenesis; mevastatin; microphthalmia-associated transcription factor.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anticholesteremic Agents / pharmacology*
Cell Line, Tumor
Cholesterol / metabolism*
Cyclic AMP / metabolism*
Lovastatin / analogs & derivatives*
Lovastatin / pharmacology
Melanins / biosynthesis*
Mice

Substances

Anticholesteremic Agents
Melanins
mevastatin
Cholesterol
Lovastatin
Cyclic AMP