Relationship between Spinal Hemangioblastoma Location and Age

Asian Spine J. 2016 Apr;10(2):309-13. doi: 10.4184/asj.2016.10.2.309. Epub 2016 Apr 15.

Abstract

Study design: Retrospective case series.

Purpose: To investigate the relationship between tumor location and clinical characteristics.

Overview of literature: Hemangioblastoma is a rare disease that develops in the central nervous system. Magnetic resonance imaging (MRI) is useful to evaluate hemangioblastomas. Hemangioblastoma's location is designated as intramedullary, intramedullary+extramedullary, or extramedullary by MRI.

Methods: We analyzed 11 patients who underwent surgery for spinal hemangioblastoma. Using T1 contrast axial MRI data, the cases were divided into three groups (intramedullary, intramedullary+extramedullary, and extramedullary). Patient demographics, MRI findings, and preoperative neurological status were analyzed and compared for each group.

Results: The average age of patients with intramedullary, intramedullary+extramedullary, and extramedullary hemangioblastoma was 34.0, 64.4, and 67.5 years, respectively. Patients in the intramedullary hemangioblastoma group were younger than the other groups. Extramedullary cases had a smaller syrinx compared to the other groups.

Conclusions: Age may play an important role in the hemangioblastoma tumor location and the subsequent diagnosis by an MRI.

Keywords: Age; Magnetic resonance imaging; Spinal hemangioblastoma; Tumor location.