Clinical outcomes of patients with peripheral artery disease and lower extremity wounds based on a predetermined intention-to-treat strategy

Semin Vasc Surg. 2015 Sep-Dec;28(3-4):184-9. doi: 10.1053/j.semvascsurg.2016.01.001. Epub 2016 Jan 6.

Abstract

Achieving healing in patients with peripheral artery disease and lower extremity wounds represent a significant clinical challenge. Important outcome measures that define a successful therapeutic approach include wound healing rate, time to heal, and recurrence with time. This article reviews our experience managing a peripheral artery disease patient cohort at a Veterans Affairs medical center based on the initial clinical evaluation stratification and prospective enrollment into a predetermined treatment strategy.

MeSH terms

  • Aged
  • Amputation, Surgical
  • California
  • Databases, Factual
  • Esophageal Sphincter, Lower / blood supply*
  • Female
  • Humans
  • Intention to Treat Analysis
  • Ischemia / diagnosis
  • Ischemia / mortality
  • Ischemia / therapy*
  • Leg Ulcer / diagnosis
  • Leg Ulcer / mortality
  • Leg Ulcer / therapy*
  • Limb Salvage
  • Male
  • Middle Aged
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / mortality
  • Peripheral Arterial Disease / therapy*
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Vascular Surgical Procedures* / adverse effects
  • Vascular Surgical Procedures* / mortality
  • Wound Healing*