Determination of uncertainties associated to the in vivo measurement of iodine-131 in the thyroid

Appl Radiat Isot. 2016 Jul:113:1-4. doi: 10.1016/j.apradiso.2016.04.007. Epub 2016 Apr 12.

Abstract

Intakes of radionuclides can be estimated through in vivo measurements, and the uncertainties associated to the measured activities should be clearly stated in monitoring program reports. This study aims to evaluate the uncertainties of in vivo monitoring of iodine 131 in the thyroid. The reference values for high-energy photons are based on the IDEAS Guide. Measurements were performed at the In Vivo Monitoring Laboratory of the Institute of Radiation Protection and Dosimetry (IRD) and at the Internal Dosimetry Laboratory of the Regional Center of Nuclear Sciences (CRCN-NE). In both institutions, the experiment was performed using a NaI(Tl) 3''3″ scintillation detector and a neck-thyroid phantom. Scattering factors were calculated and compared in different counting geometries. The results show that the technique produces reproducibility equivalent to the values suggested in the IDEAS Guide and measurement uncertainties is comparable to international quality standards for this type of in vivo monitoring.

Keywords: Iodine-131; Measurement uncertainty; Thyroid; in vivo measurement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Barium Radioisotopes / analysis
  • Humans
  • Iodine Radioisotopes / analysis*
  • Phantoms, Imaging
  • Photons
  • Radiation Monitoring / methods*
  • Radiation Monitoring / standards
  • Radiation Monitoring / statistics & numerical data
  • Reproducibility of Results
  • Scattering, Radiation
  • Scintillation Counting
  • Thyroid Gland / radiation effects*
  • Uncertainty

Substances

  • Barium Radioisotopes
  • Iodine Radioisotopes
  • Iodine-131