Gamma Radiation Reduced Toxicity of Azoxystrobin Tested on Artemia franciscana

Bull Environ Contam Toxicol. 2016 Jun;96(6):822-6. doi: 10.1007/s00128-016-1805-8. Epub 2016 Apr 23.

Abstract

Fungicide azoxystrobin toxicity was monitored by means of a 96-h biotest with Artemia franciscana nauplius stages after exposure to solutions with concentrations of 0.2, 0.4, 0.6 and 0.8 mg L(-1) irradiated with (60)Co gamma radiation with doses of 1, 2.5, 5 and 10 kGy. The effects of ionization radiation on azoxystrobin toxicity were mainly manifested by a statistically significant reduction of lethality after 72- and 96-h exposure. A maximum reduction of lethality of 72 % was achieved using doses of 1-5 kGy for an azoxystrobin initial concentration of 0.4 mg L(-1) and after 72 h of exposure. At a 96-h exposure, a difference of lethal effects reached up to 70 % for a dose of 10 kGy. The observed effect of gamma ionizing radiation on azoxystrobin toxicity suggest that this approach can be applied as an alternative for a reduction of azoxystrobin residua in food.

Keywords: 60Co gamma radiation; Biotest; Fungicide azoxystrobin; Nauplius stages Artemia franciscana.

MeSH terms

  • Animals
  • Antifungal Agents / chemistry
  • Antifungal Agents / toxicity*
  • Artemia / drug effects*
  • Artemia / radiation effects*
  • Dose-Response Relationship, Drug
  • Dose-Response Relationship, Radiation
  • Food Analysis
  • Food Contamination / analysis
  • Food Microbiology
  • Gamma Rays*
  • Lethal Dose 50
  • Methacrylates / chemistry
  • Methacrylates / toxicity*
  • Pyrimidines / chemistry
  • Pyrimidines / toxicity*
  • Radiation, Ionizing
  • Strobilurins

Substances

  • Antifungal Agents
  • Methacrylates
  • Pyrimidines
  • Strobilurins
  • azoxystrobin