Cervical Ectopic Pregnancy Complicated by Escherichia Coli Septicemia: A Case Report

J Obstet Gynaecol Can. 2016 Mar;38(3):275-8. doi: 10.1016/j.jogc.2015.12.008. Epub 2016 Mar 10.

Abstract

Background: Cervical ectopic pregnancy is an uncommon form of ectopic pregnancy. The spectrum of treatment options includes systemic medical therapy, local injection with methotrexate and/or potassium chloride, surgery, or a combination of these modalities.

Case: A 29-year-old woman, gravida 3, aborta 2, was found to have a cervical ectopic pregnancy on ultrasound at 5+6 weeks' gestation. She presented to the hospital with vaginal bleeding. Treatment was initiated with multidose methotrexate and leucovorin rescue. She subsequently developed Gram-negative septicemia, with blood cultures growing Escherichia coli. This was managed successfully by surgical removal of the ectopic pregnancy and antimicrobial therapy.

Conclusion: A cervical ectopic pregnancy can be complicated by E. coli septicemia.

Keywords: Cervical ectopic pregnancy; methotrexate; septicemia.

Publication types

  • Case Reports

MeSH terms

  • Abortifacient Agents, Nonsteroidal / therapeutic use
  • Adult
  • Cervix Uteri / diagnostic imaging
  • Cervix Uteri / pathology
  • Escherichia coli Infections* / complications
  • Escherichia coli Infections* / diagnosis
  • Female
  • Humans
  • Leucovorin / therapeutic use
  • Methotrexate / therapeutic use
  • Pregnancy
  • Pregnancy, Ectopic* / diagnostic imaging
  • Pregnancy, Ectopic* / drug therapy
  • Pregnancy, Ectopic* / pathology
  • Sepsis* / complications
  • Sepsis* / diagnosis

Substances

  • Abortifacient Agents, Nonsteroidal
  • Leucovorin
  • Methotrexate