Wormhole Travel for Macrophages

Yasutaka Okabe; Ruslan Medzhitov

doi:10.1016/j.cell.2016.04.005

Wormhole Travel for Macrophages

Cell. 2016 Apr 21;165(3):518-9. doi: 10.1016/j.cell.2016.04.005.

Authors

Yasutaka Okabe¹, Ruslan Medzhitov²

Affiliations

¹ Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA.
² Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA. Electronic address: ruslan.medzhitov@yale.edu.

PMID: 27104973
DOI: 10.1016/j.cell.2016.04.005

Abstract

Leukocyte recruitment is generally achieved by rapid migration of inflammatory cells out of circulation, through modified blood vessels, and into affected tissues. Now, Wang and Kubes show that macrophages can be rapidly recruited from body cavities to the liver, via a non-vascular route, where they help to coordinate tissue repair.

Publication types

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MeSH terms

Humans
Leukocytes*
Liver / blood supply
Macrophages*