[Clinical appearance and scalable profile Thiamine deficiency in prison in Guinea: study of thirty-eight observations]

Bull Soc Pathol Exot. 2016 May;109(2):70-6. doi: 10.1007/s13149-016-0484-3. Epub 2016 Mar 29.
[Article in French]

Abstract

Cardiovascular and neurological manifestations associated with thiamine deficiency in Guinean prisons are common but not reported.We performed a prospective study of 38 cases related to vitamin B1 deficiency over a period of 4 years. In this population, the literature of traditional data gathered: frequency peak after thirty (92.6%) and clear representation male (sex ratio M/F: 18/1). The clinical symptomatology remains essentially dominated by sensorimotor polyneuropathy and pure sensory (52.2%), overall heart failure (31.5%) and to a lesser degree by Gayet Wernicke's encephalopathy (7.8%) and shoshin beriberi with severe evolution (5.2%). The study of nutritional status by body mass index (BMI) of the World Health Organization, by the criteria of Detsky and biological markers including albumin, shows that these patients are severely malnourished.

Keywords: Clinic; EMG; Electromyography; Gayet- Wernicke’s encephalopathy; Guinea; Malnutrition; Overall heart failure; Prisons; Shoshin beriberi; Sub-Saharan Africa; Thiamine deficiency.

MeSH terms

  • Adult
  • Beriberi / diagnosis
  • Beriberi / epidemiology
  • Cohort Studies
  • Diagnosis, Differential
  • Female
  • Guinea / epidemiology
  • Humans
  • Male
  • Malnutrition / diagnosis
  • Malnutrition / epidemiology
  • Middle Aged
  • Phenotype
  • Prisoners / statistics & numerical data*
  • Prisons / statistics & numerical data
  • Thiamine Deficiency / diagnosis*
  • Thiamine Deficiency / epidemiology*
  • Wernicke Encephalopathy / diagnosis
  • Wernicke Encephalopathy / epidemiology