For healing wounds, burns and ulcers has a great impact on economy. New medications, technologies and other interventions are being used for skin injuries and to eliminate infections. Despite several technological and strategic advances in this field, wound care has returned to the roots of medicine and some of the remedies used millennia ago have been studied at present. This review gives an awareness of commercially available drugs to healing of wounds from natural origin. The research was conducted based on the requests for patents deposited in the Espacenet (European Patent Office) and in the WIPO (World Intellectual Property Organization). The research focused on exploring the uses of medicinal plants/natural products as a therapeutic approach to wounds and burns healing. Further, this study discusses the recent trends in the usage of natural products in topical formulations and the patents on it were reviewed, in addition to, future investigations and application of natural products in healing of wounds. Natural products have great therapeutic potential and should be used in the development of new products for the treatment of skin injuries.