Comparison of Cepheid Xpert Flu/RSV XC and BioFire FilmArray for Detection of Influenza A, Influenza B, and Respiratory Syncytial Virus

Mark G Wahrenbrock; Scott Matushek; Sue Boonlayangoor; Vera Tesic; Kathleen G Beavis; Angella Charnot-Katsikas

doi:10.1128/JCM.00084-16

Comparison of Cepheid Xpert Flu/RSV XC and BioFire FilmArray for Detection of Influenza A, Influenza B, and Respiratory Syncytial Virus

J Clin Microbiol. 2016 Jul;54(7):1902-1903. doi: 10.1128/JCM.00084-16. Epub 2016 Apr 20.

Authors

Mark G Wahrenbrock¹, Scott Matushek¹, Sue Boonlayangoor¹, Vera Tesic¹, Kathleen G Beavis¹, Angella Charnot-Katsikas²

Affiliations

¹ Department of Pathology, The University of Chicago Medicine, Chicago, Illinois, USA.
² Department of Pathology, The University of Chicago Medicine, Chicago, Illinois, USA angella.charnot-katsikas@uchospitals.edu.

Abstract

The Xpert Flu/RSV XC was compared to the FilmArray respiratory panel for detection of influenza (Flu) A, Flu B, and respiratory syncytial virus (RSV), using 128 nasopharyngeal swabs. Positive agreements were 100% for Flu A and RSV and 92.3% for Flu B. The Xpert may be useful in clinical situations when extensive testing is not required and may serve an important role in laboratories already performing broader respiratory panel testing.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Female
Humans
Infant
Influenza A virus / isolation & purification*
Influenza B virus / isolation & purification*
Influenza, Human / diagnosis*
Male
Middle Aged
Molecular Diagnostic Techniques / methods*
Nasopharynx / virology
Respiratory Syncytial Virus Infections / diagnosis*
Respiratory Syncytial Viruses / isolation & purification*
Young Adult