The goal of the current study was to validate a new measure of the friendship self-disclosure process that assesses the likelihood of disclosing a negative peer experience and expectations for friends' responses to disclosure (EFRD) of this experience. Participants for Study 1 were 572 adolescents (age M = 14.82; 53% female; 66% Caucasian) from a public school sample who completed the self-disclosure survey and a measures of depressive symptoms at one time point. Participants of Study 2 comprised 180 obese adolescents (age M = 12.78; 67% female; 58% African American) from an urban children's hospital. The obese sample completed the self-disclosure survey, as well as measures of friendship quality, peer victimization, and depressive symptoms at two time points, 6 months apart. For both studies, 3 dimensions of EFRD were examined: protection, blame, and negative responses. Each EFRD dimension was replicated across 2 samples, over time, and had good interitem reliability as well as convergent and discriminant validity. In Study 2, high rates of expected negativity (only for boys) and blame (for boys and girls) predicted increases in depressive symptoms. In addition, victimization led to increases in depression for obese adolescents who expected little in the way of protective responses from their friends. In contrast, changes in depression were not predictable from victimization for those who expected friends to use protective responses. EFRD are clearly important mechanisms in the self-disclosure process that may serve to protect against changes in adjustment in response to negative peer experiences, such as peer victimization.