Abstract
A new flavonoid glycoside, eriodictyol 7-O-(6″-caffeoyl)-β-D-glucopyranoside (1), along with 14 known compounds, were isolated from the whole plants of Elsholtzia bodinieri. All of the structures were determined by spectroscopic methods and chemical transformation. Compound 1 and luteolin (9) exhibited potent anti-HCV activities with a selective index of 135.85 and 20.84, respectively.
Keywords:
Elsholtzia bodinieri; anti-HCV activities; flavanone; labiatae.
MeSH terms
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology
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Drug Evaluation, Preclinical / methods
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Flavones / isolation & purification*
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Flavones / pharmacology*
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology*
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Glucosides / isolation & purification*
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Glucosides / pharmacology*
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Glycosides / chemistry
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Glycosides / isolation & purification
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Glycosides / pharmacology
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Hepacivirus / drug effects
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Lamiaceae / chemistry*
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Luteolin / pharmacology
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Molecular Structure
Substances
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Antiviral Agents
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Flavones
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Flavonoids
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Glucosides
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Glycosides
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eriodictyol 7-O-(6'-caffeoyl)glucopyranoside
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Luteolin