Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome

Eur J Pharmacol. 2016 Aug 15:785:207-214. doi: 10.1016/j.ejphar.2016.04.021. Epub 2016 Apr 12.

Abstract

The metabolic syndrome is a group of obesity associated metabolic conditions that result in increased risk of cardiovascular disease and type 2 diabetes. Global increases in obesity rates have led to an increase in metabolic syndrome resulting in a demand for increased understanding of the mechanisms involved. This review examines the relationship between adipose tissue biology, lipid metabolism and chronic low grade inflammation relating to obesity and insulin resistance.

Keywords: Fatty acids; Inflammation; Metabolic syndrome; Obesity.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / metabolism
  • Animals
  • Chronic Disease
  • Fatty Acids / metabolism*
  • Humans
  • Inflammation / complications
  • Metabolic Syndrome / complications
  • Metabolic Syndrome / metabolism*
  • Metabolic Syndrome / pathology
  • Obesity / complications
  • Obesity / metabolism*
  • Obesity / pathology

Substances

  • Fatty Acids