Correlations between obesity indices and cardiometabolic risk factors in obese subgroups in women with severe obesity: A multicenter, cross-sectional study

Seung Hun Lee; Young Jin Tak; Yu Hyeon Yi; Sang Yeoup Lee; Young Hye Cho; Jeong Gyu Lee; Yun Jin Kim; Hwang Hye Rim; Kyung Won Shim; Sung Soo Kim; Sang Woo Oh

doi:10.1016/j.orcp.2016.03.014

Correlations between obesity indices and cardiometabolic risk factors in obese subgroups in women with severe obesity: A multicenter, cross-sectional study

Obes Res Clin Pract. 2017 Mar-Apr;11(2):167-176. doi: 10.1016/j.orcp.2016.03.014. Epub 2016 Apr 11.

Authors

Affiliations

¹ Department of Family Medicine, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan-si 602-739, South Korea.
² Medical Education Unit and Medical Research Institute Pusan National University School of Medicine, Yangsan 626-780, South Korea; Obesity, Nutrition and Metabolism Clinic, Department of Family Medicine and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 626-770, South Korea. Electronic address: saylee@pnu.edu.
³ Obesity, Nutrition and Metabolism Clinic, Department of Family Medicine and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 626-770, South Korea.
⁴ Department of Family Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea.
⁵ Department of Family Medicine, Chungnam National University School of Medicine, Daejeon, South Korea.
⁶ Department of Family Medicine, Center for Obesity, Metabolism, and Clinical Nutrition, Dongguk University International Hospital, South Korea.

PMID: 27079120
DOI: 10.1016/j.orcp.2016.03.014

Abstract

Background: To investigate associations between degrees of obesity using correlations between obesity indices and cardiometabolic risk factors in women.

Methods: BMI, waist circumference (WC), fasting insulin, fasting glucose, lipids, and visceral adipose tissue (VAT) area using computed tomographic images were measured in 113 women with obesity. Correlations between obesity indices and cardiometabolic risk factors were analyzed in subgroups defined using sequential obesity indices.

Results: Mean BMI and WC were 29.6kg/m² and 92.8cm. BMI showed significant correlations with all five cardiometabolic risk factors until the BMI cut-off point reached 29kg/m², but when it exceeded 30kg/m², correlations no longer existed. WC was significantly correlated with all five cardiometabolic risk factors up to a value of 85cm, but when WC exceeded 90cm, correlations no longer existed.

Conclusions: Our cross-sectional study suggest that significant correlations between obesity indices and cardiometabolic risk factors may disappear, when obesity cut-off points exceed certain limits in women.

Keywords: Cardiovascular disease risk; Insulin resistance; Metabolic disease; Obesity; Risk factors.

Publication types

Multicenter Study

MeSH terms

Adult
Blood Glucose*
Body Mass Index*
Cross-Sectional Studies
Female
Humans
Insulin / blood*
Intra-Abdominal Fat / diagnostic imaging*
Middle Aged
Obesity, Morbid / diagnostic imaging
Obesity, Morbid / metabolism*
Risk Factors
Waist Circumference / physiology*

Substances

Blood Glucose
Insulin