Initial and mid-term results from 108 consecutive patients with cerebral aneurysms treated with the WEB device

J Neurointerv Surg. 2017 Apr;9(4):411-417. doi: 10.1136/neurintsurg-2016-012276. Epub 2016 Apr 13.

Abstract

Introduction: The Woven EndoBridge (WEB) is a novel device for the treatment of wide-necked intracranial bifurcation aneurysms. The present series demonstrates our 'real-world experience' in the use of all iterations of WEB devices (available in Europe) in ruptured and unruptured aneurysms.

Methods: We analyzed our all-inclusive cerebrovascular database for patients treated with the WEB device between October 2010 and May 2015. Anatomic and clinical results are reported for all patients.

Results: One hundred and eight patients with 114 intracranial aneurysms were included in the series. Forty-seven aneurysms (41.2%) were ruptured. Eighty-six patients received angiographic and clinical follow-up after a mean of 13.4 months. One hundred and ten of 114 WEB devices (96.5%) were deployed successfully. Thromboembolic complications occurred in 11 of 110 interventions (10.0%), with a new permanent deficit in one patient. Re-rupture after WEB treatment was detected in two aneurysms (4.3%), which had both initially presented with subarachnoid hemorrhage. Angiographic follow-up revealed adequate occlusion in 68 of 90 aneurysms (75.6%). Fifteen aneurysms required retreatment.

Conclusions: This series confirms a high level of safety and efficacy of the WEB device for the treatment of wide-necked intracranial aneurysms.

Keywords: Aneurysm; Device; Flow Diverter; Hemorrhage.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / therapy*
  • Cerebral Angiography
  • Disability Evaluation
  • Embolization, Therapeutic / instrumentation*
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / therapy*
  • Male
  • Middle Aged
  • Recurrence
  • Retreatment
  • Retrospective Studies
  • Thromboembolism / etiology
  • Treatment Outcome