Koelliker haemoglobins in developing chick embryo

Comp Biochem Physiol B. 1989;92(1):103-9. doi: 10.1016/0305-0491(89)90320-9.

Abstract

1. Three Koelliker haemoglobins, HbKE, HbKA and HbKH, derived from a post-translational loss of alpha-Arg-141, were isolated from red cells of chicken embryos. HbKE is typical of embryos up to 7 days of incubation, HbKA and HbKH are found in mature embryos. 2. All the precursor haemoglobins contain alpha A chains. HbKA derives from adult haemoglobin A whose globin composition is alpha A2 beta 2, HbKH from embryonic haemoglobin H with a globin composition alpha A2 beta H2 and HbKE from embryonic haemoglobin E with globin composition alpha A2 epsilon 2. 3. No Koelliker derivatives of haemoglobins with alpha-like chains other than alpha A were observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carboxymethylcellulose Sodium
  • Chick Embryo / analysis*
  • Chick Embryo / growth & development
  • Chromatography
  • Electrophoresis, Polyacrylamide Gel
  • Globins / isolation & purification
  • Hemoglobins, Abnormal / isolation & purification*
  • Protein Processing, Post-Translational

Substances

  • Hemoglobins, Abnormal
  • hemoglobin Koelliker
  • Globins
  • Carboxymethylcellulose Sodium