Lost at Sea in Search of a Diagnosis: A Case of Unexplained Bleeding

Pediatr Blood Cancer. 2016 Jul;63(7):1305-6. doi: 10.1002/pbc.25980. Epub 2016 Apr 8.

Abstract

Scurvy results from a dietary deficiency of vitamin C (ascorbic acid) and is rarely thought of in modern day medicine. It now almost always occurs in pediatric patients with behavioral diagnoses, nutritionally restricted diets, and food allergies. Symptoms of scurvy include ecchymoses, bleeding gums, and arthralgias. Here, we present a 17-year-old male with autism spectrum disorder and a diet severely deficient in ascorbic acid due to textural aversion and food preferences. He presented with recurrent arthritis, hemarthrosis, bruising, and anemia. His vitamin C level was low, and his symptoms improved promptly after treatment with ascorbic acid.

Keywords: autism spectrum disorder; hemarthrosis; scurvy.

MeSH terms

  • Adolescent
  • Ascorbic Acid / administration & dosage*
  • Autism Spectrum Disorder*
  • Hemorrhage* / diagnosis
  • Hemorrhage* / drug therapy
  • Hemorrhage* / pathology
  • Humans
  • Male
  • Scurvy* / diagnosis
  • Scurvy* / drug therapy
  • Scurvy* / pathology

Substances

  • Ascorbic Acid