Idelalisib-Rituximab induces clinical remissions in patients with TP53 disrupted B cell prolymphocytic leukaemia

Br J Haematol. 2017 May;177(3):486-491. doi: 10.1111/bjh.14066. Epub 2016 Apr 7.
No abstract available

Keywords: TP53; B-cell prolymphocytic leukaemia; TP53 deletion; idelalisib; prolymphocytic leukaemia.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Comorbidity
  • Genetic Variation*
  • Humans
  • Leukemia, Prolymphocytic, B-Cell / diagnosis
  • Leukemia, Prolymphocytic, B-Cell / drug therapy*
  • Leukemia, Prolymphocytic, B-Cell / genetics*
  • Phenotype
  • Purines / administration & dosage
  • Quinazolinones / administration & dosage
  • Rituximab / administration & dosage
  • Treatment Outcome
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Purines
  • Quinazolinones
  • Tumor Suppressor Protein p53
  • Rituximab
  • idelalisib