Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA)

Malathi Narayan; Kent W Seeley; Umesh K Jinwal

doi:10.1016/j.dib.2016.03.026

Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA)

Data Brief. 2016 Mar 14:7:747-50. doi: 10.1016/j.dib.2016.03.026. eCollection 2016 Jun.

Authors

Malathi Narayan¹, Kent W Seeley², Umesh K Jinwal¹

Affiliations

¹ Department of Pharmaceutical Sciences, College of Pharmacy, Byrd Alzheimer׳s Institute, University of South Florida-Health, 4001 E. Fletcher Ave, MDC36, Tampa, FL 33613, USA.
² Florida Center of Excellence for Drug Discovery & Innovation at the University of South Florida, 3720 Spectrum Blvd., Suite 303, IDR Building, Tampa, FL 33612, USA.

Abstract

Mass spectrometry data collected in a study analyzing the effect of withaferin A (WA) on a mouse microglial (N9) cell line is presented in this article. Data was collected from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with either WA or DMSO vehicle control. This article reports all the proteins that were identified in this analysis. The data presented here is related to the published research article on the effect of WA on the differential regulation of proteins in mouse microglial cells [1]. Mass spectrometry data has also been deposited in the ProteomeXchange with the identifier PXD003032.

Keywords: Mass spectrometry; Microglial cell line; Proteomics; SILAC; Withaferin A.