Genome analysis of an atypical bovine pestivirus from fetal bovine serum

Virus Genes. 2016 Aug;52(4):561-3. doi: 10.1007/s11262-016-1321-2. Epub 2016 Apr 6.

Abstract

We report the complete genome sequence of a bovine pestivirus LVRI/cont-1 originated from a commercial batch of fetal bovine serum. Its complete genome consists of 12,282 nucleotides (nt), which contain an open reading frame (ORF) of 11,700 bp flanked by 5' and 3' untranslated regions (383 and 199 bp). The size of the 5'UTR and the individual protein coding region of LVRI/cont-1 are identical to those of the reference virus Th/04_KhonKaen, but it has a deletion of the first 56 nt in the 3'UTR. Alignment of the complete nucleotide sequence and phylogenetic analysis indicate that this viral isolate belongs to atypical pestiviruses.

Keywords: Atypical bovine pestivirus; Genome; Phylogeny.

MeSH terms

  • 3' Untranslated Regions / genetics
  • 5' Untranslated Regions / genetics
  • Animals
  • Base Sequence / genetics
  • Cattle
  • Diarrhea Viruses, Bovine Viral / genetics*
  • Genome, Viral / genetics*
  • Open Reading Frames / genetics
  • Phylogeny
  • RNA, Viral / genetics
  • Sequence Alignment

Substances

  • 3' Untranslated Regions
  • 5' Untranslated Regions
  • RNA, Viral