Abstract
Two new ursane-type triterpenes characterized as 3-oxo-24-acetoxy-11α-hydroxy-urs-12-ene (1) and methyl 3α-acetoxy-11α-methoxy-urs-12-en-24-oate (2), together with known compounds 3-11, were isolated from Boswellia rivae oleo-gum resin exudate. Their structural elucidation was accomplished using physical, chemical, and spectroscopic methods. The compounds exhibited weak to moderate antibacterial activities against some Gram-positive and Gram-negative bacteria.
Keywords:
Boswellia rivae; Burseraceae; antibacterial activities; terpenoids.
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Boswellia / chemistry*
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Electron Spin Resonance Spectroscopy
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Gram-Negative Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Kenya
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Microbial Sensitivity Tests
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Molecular Structure
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Resins, Plant / chemistry*
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Triterpenes / chemistry*
Substances
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3-oxo-24-acetoxy-11alpha-hydroxy-urs-12-ene
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Anti-Bacterial Agents
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Resins, Plant
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Triterpenes
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methyl 3alpha-acetoxy-11alpha-methoxy-urs-12-en-24-oate
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tirucallane
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ursane