Abstract
We have described a new class of hydrogelator based on helical β(3)-peptides carrying a bioactive payload. The β(3)-peptides self-assemble in aqueous solution to form a nanofibrous mesh resulting in a stable hydrogel. The simple design provides the versatility for attaching different functional payloads to the β(3)-peptide scaffold to develop new materials.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Adhesion / drug effects
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Cell Line
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Elasticity
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Hydrogels / chemical synthesis*
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Hydrogels / pharmacology
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Lipopeptides / chemical synthesis*
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Lipopeptides / pharmacology
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Mice
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Oligopeptides / chemical synthesis*
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Oligopeptides / pharmacology
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Rheology
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Viscosity
Substances
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Hydrogels
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Lipopeptides
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Oligopeptides
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arginyl-glycyl-aspartic acid