Preoperative Prophylactic Intraaortic Balloon Pump Reduces the Incidence of Postoperative Acute Kidney Injury and Short-Term Death of High-Risk Patients Undergoing Coronary Artery Bypass Grafting: A Meta-Analysis of 17 Studies

Ann Thorac Surg. 2016 May;101(5):2007-19. doi: 10.1016/j.athoracsur.2015.10.078. Epub 2016 Apr 1.

Abstract

This meta-analysis investigated the effects of preoperative prophylactic intraaortic balloon pump placement on postoperative renal function and short-term death of high-risk patients undergoing coronary artery bypass grafting. We found that preoperative prophylactic intraaortic balloon pump support reduced the incidence of coronary artery bypass grafting-associated acute kidney injury and short-term death and dramatically decreased the incidence of postoperative renal replacement therapy by 82% compared with high-risk patients without the procedure. This is the first meta-analysis to demonstrate significant beneficial effects of preoperative prophylactic intraaortic balloon pump on renal function in high-risk patients undergoing coronary artery bypass grafting.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Acute Kidney Injury / epidemiology
  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / prevention & control*
  • Acute Kidney Injury / therapy
  • Clinical Trials as Topic
  • Coronary Artery Bypass*
  • Coronary Artery Bypass, Off-Pump
  • Hospital Mortality
  • Humans
  • Intra-Aortic Balloon Pumping*
  • Odds Ratio
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control*
  • Postoperative Complications / therapy
  • Preoperative Care / methods*
  • Renal Replacement Therapy / statistics & numerical data
  • Risk Factors