Role of Bile Acid-Regulated Nuclear Receptor FXR and G Protein-Coupled Receptor TGR5 in Regulation of Cardiorenal Syndrome (Cardiovascular Disease and Chronic Kidney Disease)

Hypertension. 2016 Jun;67(6):1080-4. doi: 10.1161/HYPERTENSIONAHA.115.06417. Epub 2016 Apr 4.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Cardio-Renal Syndrome* / metabolism
  • Cardio-Renal Syndrome* / physiopathology
  • Cardio-Renal Syndrome* / therapy
  • Diabetes Mellitus / diagnosis
  • Diabetes Mellitus / metabolism
  • Disease Progression
  • Humans
  • Lipid Metabolism / drug effects
  • Obesity / diagnosis
  • Obesity / metabolism
  • Prognosis
  • Receptors, Cytoplasmic and Nuclear* / agonists
  • Receptors, Cytoplasmic and Nuclear* / physiology
  • Receptors, G-Protein-Coupled* / agonists
  • Receptors, G-Protein-Coupled* / physiology

Substances

  • GPBAR1 protein, human
  • Receptors, Cytoplasmic and Nuclear
  • Receptors, G-Protein-Coupled
  • farnesoid X-activated receptor