The Point-of-Care Laboratory in Clinical Microbiology

Clin Microbiol Rev. 2016 Jul;29(3):429-47. doi: 10.1128/CMR.00090-15.

Abstract

Point-of-care (POC) laboratories that deliver rapid diagnoses of infectious diseases were invented to balance the centralization of core laboratories. POC laboratories operate 24 h a day and 7 days a week to provide diagnoses within 2 h, largely based on immunochromatography and real-time PCR tests. In our experience, these tests are conveniently combined into syndrome-based kits that facilitate sampling, including self-sampling and test operations, as POC laboratories can be operated by trained operators who are not necessarily biologists. POC laboratories are a way of easily providing clinical microbiology testing for populations distant from laboratories in developing and developed countries and on ships. Modern Internet connections enable support from core laboratories. The cost-effectiveness of POC laboratories has been established for the rapid diagnosis of tuberculosis and sexually transmitted infections in both developed and developing countries.

Publication types

  • Review

MeSH terms

  • Communicable Diseases / diagnosis*
  • Cost-Benefit Analysis
  • Developed Countries
  • Developing Countries
  • Early Diagnosis
  • Humans
  • Point-of-Care Systems / economics
  • Point-of-Care Systems / organization & administration*
  • Reagent Kits, Diagnostic

Substances

  • Reagent Kits, Diagnostic