Palladium-catalyzed C(sp(3))-C(sp(2)) cross-coupling of homoleptic rare-earth metal trialkyl complexes with aryl bromides: efficient synthesis of functionalized benzyltrimethylsilanes

Guilong Cai; Yingda Huang; Tingting Du; Shaowen Zhang; Bo Yao; Xiaofang Li

doi:10.1039/c6cc01312k

Palladium-catalyzed C(sp(3))-C(sp(2)) cross-coupling of homoleptic rare-earth metal trialkyl complexes with aryl bromides: efficient synthesis of functionalized benzyltrimethylsilanes

Chem Commun (Camb). 2016 Apr 7;52(31):5425-7. doi: 10.1039/c6cc01312k.

Authors

Guilong Cai¹, Yingda Huang¹, Tingting Du¹, Shaowen Zhang¹, Bo Yao¹, Xiaofang Li¹

Affiliation

¹ Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, China. yaobo@bit.edu.cn xfli@bit.edu.cn.

PMID: 27009850
DOI: 10.1039/c6cc01312k

Abstract

The first C(sp(3))-C(sp(2)) cross-coupling of rare-earth metal alkyl complexes with aryl bromides has been developed. This reaction was conducted at low catalyst loading (0.5 mol%) and exhibited a broad substrate scope, thus providing a facile method for the synthesis of benzyltrimethylsilanes with diverse functional groups.

Publication types

Research Support, Non-U.S. Gov't