BODIPY-containing nanoscale metal-organic frameworks for photodynamic therapy

Weiqi Wang; Lei Wang; Zhensheng Li; Zhigang Xie

doi:10.1039/c6cc01048b

BODIPY-containing nanoscale metal-organic frameworks for photodynamic therapy

Chem Commun (Camb). 2016 Apr 7;52(31):5402-5. doi: 10.1039/c6cc01048b.

Authors

Weiqi Wang¹, Lei Wang², Zhensheng Li², Zhigang Xie²

Affiliations

¹ State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. leiwang@ciac.ac.cn xiez@ciac.ac.cn and The University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
² State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China. leiwang@ciac.ac.cn xiez@ciac.ac.cn.

PMID: 27009757
DOI: 10.1039/c6cc01048b

Abstract

BODIPY-immobilized zirconium-based nanoscale metal-organic frameworks (MOFs), named , have been synthesized through solvent-assisted ligand exchange using UiO-typed MOFs and pre-designed BODIPY ligands for the first time. The nanocrystal has been proved to possess good biocompatibility and highly efficient generation of singlet oxygen, which could kill the cancer cells effectively.

Publication types

Research Support, Non-U.S. Gov't